Indole 3 Carbinol is a compound found in cruciferous vegetables such as cabbage, broccoli, kale and cauliflower. Since being discovered, Indole 3 Carbinol has been used in many studies that suggest several health benefits, especially for women. Oral ingestion of Indole 3 Carbinol has been shown to alter the metabolism of estrogen in a beneficial manner.
Both male and female bodies have estrogen receptors. These receptors are like electrical outlets. The purpose of estrogen receptors is to receive estrogen and allow the body to process the estrogen. Just like there are many different things that you could plug into an electrical outlet, there are several different types of estrogen that can plug into estrogen receptors.
Different forms of estrogen have different effects when plugged into those estrogen receptors. The weaker the estrogen, the less estrogenic effects they will have on the body. The stronger the estrogen, the more negative effects they will have on health.
Ideally we want to plug as many estrogen receptors as possible with weak estrogens. HRT and hormonal birth control methods all use the strongest natural estrogen. Indole 3 Carbinol mimics the weakest forms of estrogen. Therefore, the more Indole 3 Carbinol that is absorbed by the body and used to plug the estrogen receptors, less receptors will be available to the stronger estrogens.
In comparison with the popular anti-estrogen drug tamoxifen which is sixty percent effective against estrogen promoted breast cancer cells, Indole 3 Carbinol is ninety percent effective. When put to the test at the National Cancer Institute, indole-3-carbinol was found to be the most effective anti-cancer agent among eighty substances that were tested. Studies have also indicated that Indole 3 Carbinol was beneficial to mice suffering from Lupus and other autoimmune disorders.
Other studies indicate that Indole 3 Carbinol may be beneficial for Ovarian, Prostate, and Colon cancers, HPV, and Cervical Dysplasia.
In order benefit from the cancer fighting power of Indole 3 Carbinol, experts recommend a daily intake of between 200 and 400 mg, which is the range used in clinical trial for cancer prevention. Obtaining this amount from your diet may prove to be challenging.